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Data on common carotid artery occlusion inducing focalized stroke lesions after Pertussis toxin injection.


ABSTRACT: This article contains raw and processed data related to research published by Vega et al. (2022). This complementary dataset provides further insight into the experimental validation of a single common carotid artery occlusion (CCAO) model upon pretreatment with pertussis toxin (PTX). We present data showing the extent of different PTX concentrations on neurological severity measured by Bederson score following CCAO. In addition, data indicate a protective effect of isoflurane on cerebral infarction and neurological deficits, as well as the consequences of PTX pretreatment on reperfusion after occlusion using time-of-flight magnetic resonance angiography. With these data, we aim to provide detailed experimental settings of this newly described model.

SUBMITTER: Leiss V 

PROVIDER: S-EPMC9823129 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature

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Data on common carotid artery occlusion inducing focalized stroke lesions after Pertussis toxin injection.

Leiss Veronika V   Piekorz Roland P RP   Vega Salvador Castaneda SC   Jacoby Christoph C   Flögel Ulrich U   Pexa Katja K   Schrader Jürgen J   Pichler Bernd J BJ   Beer-Hammer Sandra S   Nürnberg Bernd B  

Data in brief 20221225


This article contains raw and processed data related to research published by Vega et al. (2022). This complementary dataset provides further insight into the experimental validation of a single common carotid artery occlusion (CCAO) model upon pretreatment with pertussis toxin (PTX). We present data showing the extent of different PTX concentrations on neurological severity measured by Bederson score following CCAO. In addition, data indicate a protective effect of isoflurane on cerebral infarc  ...[more]

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