Synthesis, Properties and Spatial Structure of 4-[(3,5-Dimethyl-1,2-oxazol-4-yl)sulfonyl]cytisine.

ABSTRACT: This article has studied the synthesis of a new derivative of the known alkaloid cytisine contained in the seeds of plants of Cytisus laburnum L. and Thermopsis lanceolata R.Br., both of the Lugiminosae family. The new compound has been obtained from two biologically active compounds, such as isoxazole and cytisine. It has been demonstrated that the reaction led to the single-stage method under very mild conditions to obtain 4-[(3,5-dimethyl-1,2-oxazol-4-yl)sulfonyl]cytisine. This class of compounds is promising for obtaining the new biologically active compounds. This article has examined, in detail, a structure with using the ¹H and ¹³C NMR and two-dimensional NMR spectroscopy of COSY (¹H-¹H), HMQC (¹H-¹³C) and HMBC (

SUBMITTER: Ibrayev MK 

PROVIDER: S-EPMC9823373 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature