Portable Prussian Blue-Based Sensor for Bacterial Detection in Urine.

ABSTRACT: Bacterial infections can affect the skin, lungs, blood, and brain, and are among the leading causes of mortality globally. Early infection detection is critical in diagnosis and treatment but is a time- and work-consuming process taking several days, creating a hitherto unmet need to develop simple, rapid, and accurate methods for bacterial detection at the point of care. The most frequent type of bacterial infection is infection of the urinary tract. Here, we present a wireless-enabled, portable, potentiometric sensor for E. coli. E. coli was chosen as a model bacterium since it is the most common cause of urinary tract infections. The sensing principle is based on reduction of Prussian blue by the metabolic activity of the bacteria, detected by monitoring the potential of t

SUBMITTER: Psotta C 

PROVIDER: S-EPMC9823789 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature