Biocompatibility and Mechanical Properties of Carboxymethyl Chitosan Hydrogels

ABSTRACT: Hydrogels have the properties of solid substances and are useful for medicine, e.g., in systems for the controlled release of drugs or as wound dressings. They isolate the wound from the external environment and constitute a barrier to microorganisms while still being permeable to oxygen. In the current study, hydrogels were formed from concentrated aqueous solutions of carboxymethyl chitosan (CMCS) via electron beam irradiation, with the presence of a crosslinking agent: poly(ethylene glycol)diacrylate. The aim of the study was to compare the properties and action of biopolymer CMCS hydrogels with commercial ones and to select the best compositions for future research towards wound-dressing applications. The elasticity of the gel depended on the component concentrations and the irradiatio

SUBMITTER: Kłosinski K 

PROVIDER: S-EPMC9823898 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature