Dissolution Behaviour of Metal-Oxide Nanomaterials in Various Biological Media.

ABSTRACT: Toxicological effects of metal-oxide-engineered nanomaterials (ENMs) are closely related to their distinct physical-chemical properties, especially solubility and surface reactivity. The present study used five metal-oxide ENMs (ZnO, MnO₂, CeO₂, Al₂O₃, and Fe₂O₃) to investigate how various biologically relevant media influenced dissolution behaviour. In both water and cell culture medium (DMEM), the metal-oxide ENMs were more soluble than their bulk analogues, with the exception that bulk-MnO₂ was slightly more soluble in water than nano-MnO₂ and Fe₂O₃ displayed negligible solubility across all tested media (regardless of particle size). Lowering the initial concentration (10 mg/L

SUBMITTER: Avramescu ML 

PROVIDER: S-EPMC9824292 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature