Chemical and Biological Evaluation of Amazonian Medicinal Plant Vouacapoua americana Aubl.

ABSTRACT: Vouacapoua americana (Fabaceae) is an economically important tree in the Amazon region and used for its highly resistant heartwood as well as for medicinal purposes. Despite its frequent use, phytochemical investigations have been limited and rather focused on ecological properties than on its pharmacological potential. In this study, we investigated the phytochemistry and bioactivity of V. americana stem bark extract and its constituents to identify eventual lead structures for further drug development. Applying hydrodistillation and subsequent GC-MS analysis, we investigated the composition of the essential oil and identified the 15 most abundant components. Moreover, the diterpenoids deacetylchagresnone (1), cassa-13(14),15-dien-oic acid (2), isoneocaesalpin

SUBMITTER: Cicek SS 

PROVIDER: S-EPMC9824835 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature