Cardiometabolic Traits in Adult Twins: Heritability and BMI Impact with Age.

ABSTRACT:

Background

The prevalence of obesity and cardiometabolic diseases continues to rise globally and obesity is a significant risk factor for cardiometabolic diseases. However, to our knowledge, evidence of the relative roles of genes and the environment underlying obesity and cardiometabolic disease traits and the correlations between them are still lacking, as is how they change with age.

Method

Data were obtained from the Chinese National Twin Registry (CNTR). A total of 1421 twin pairs were included. Univariate structural equation models (SEMs) were performed to evaluate the heritability of BMI and cardiometabolic traits, which included blood hemoglobin A1c (HbA1c), fasting blood glucose (FBG), systolic blood pressure (SBP), diastolic blood pressure (DBP), total cholesterol

SUBMITTER: Hong X 

PROVIDER: S-EPMC9824881 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature