Lidocaine transdermal patches reduced pain intensity in neuropathic cancer patients already receiving opioid treatment.

ABSTRACT:

Background

Limited efficacy has been observed when using opioids to treat neuropathic pain. Lidocaine patches reduce neuropathic pain in postherpetic neuralgia, but their benefits for cancer-related neuropathic pain remain unclear. This study aimed to investigate a treatment for cancer-related neuropathic pain.

Methods

We conducted a prospective, open-label, single-arm study to assess the efficacy and safety of lidocaine transdermal patches in patients experiencing localized, superficial, neuropathic cancer pain. Terminal cancer patients already receiving opioid treatment participated in the 3-day study. The primary endpoint was pain intensity evaluated by the numerical rating scale (NRS). The secondary endpoints were the pain relief score and the quality of analgesic treatm

SUBMITTER: Tsai JH 

PROVIDER: S-EPMC9824981 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature