Retrospective validation of bone risk stratification criteria for men with de novo metastatic hormone-naive prostate cancer in China

ABSTRACT:

Background

Bone metastasis has been suggested to be a significant impactor on the prognosis of newly diagnosed de novo metastatic hormone-sensitive prostate cancer (mHSPC), and some risk stratification models have been proposed on the basis of this hypothesis. However, the effectiveness of these risk stratification criteria has not been fully evaluated in China. This study aimed to evaluate the effectiveness of the risk stratification models in China.

Methods

A total of 140 patients who were newly diagnosed with metastatic prostate cancer followed by primary androgen deprivation-based therapy from January 2008 to June 2021 at our institution were enrolled in this study. The patients were divided into different groups on the basis of high- and low-volume disease (H/LVD) cr

SUBMITTER:  

PROVIDER: S-EPMC9825052 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature