Outcomes in small children on Berlin Heart EXCOR support: age and body surface area as clinical predictive factors.

ABSTRACT:

Objectives

The Berlin Heart EXCOR (BHE) offers circulatory support across all paediatric ages. Clinically, the necessary care and the outcomes differ in various age groups. The EUROMACS database was used to study age- and size-related outcomes for this specific device.

Methods

All patients <19 years of age from the EUROMACS database supported with a BHE between 2000 and November 2021 were included. Maximally selected rank statistics were used to determine body surface area (BSA) cut-off values. Multivariable Cox proportional hazard regression using ridge penalization was performed to identify factors associated with outcomes.

Results

In total, 303 patients were included [mean age: 2.0 years (interquartile range: 0.6-8.0, males: 48.5%)]. Age and BSA were not significan

SUBMITTER: Rohde S 

PROVIDER: S-EPMC9825200 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature