The effect of the menstrual cycle on the circulating microRNA pool in human plasma: a pilot study.

ABSTRACT:

Study question

Do ovarian hormone changes influence the levels of cell-free or circulating microRNA (cf-miRNA) across the menstrual cycle?

Summary answer

This exploratory study suggests that fluctuations in hormonal levels throughout the menstrual cycle may alter cf-miRNAs levels.

What is known already

cf-miRNA levels vary with numerous pathological and physiological conditions in both males and females and are regulated by exogenous and endogenous factors, including hormones.

Study design, size, duration

A prospective, monocentric study was conducted between March and November 2021. Since this was a pilot study, the sample size was based on feasibility as well as previous similar human studies conducted in different tissues. A total of 20 participants were rec

SUBMITTER: Lamon S 

PROVIDER: S-EPMC9825267 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature