TIMEDB: tumor immune micro-environment cell composition database with automatic analysis and interactive visualization.

ABSTRACT: Deciphering the cell-type composition in the tumor immune microenvironment (TIME) can significantly increase the efficacy of cancer treatment and improve the prognosis of cancer. Such a task has benefited from microarrays and RNA sequencing technologies, which have been widely adopted in cancer studies, resulting in extensive expression profiles with clinical phenotypes across multiple cancers. Current state-of-the-art tools can infer cell-type composition from bulk expression profiles, providing the possibility of investigating the inter-heterogeneity and intra-heterogeneity of TIME across cancer types. Much can be gained from these tools in conjunction with a well-curated database of TIME cell-type composition data, accompanied by the corresponding clinical information. However, currentl

SUBMITTER: Wang X 

PROVIDER: S-EPMC9825442 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature