EmAtlas: a comprehensive atlas for exploring spatiotemporal activation in mammalian embryogenesis.

ABSTRACT: The emerging importance of embryonic development research rapidly increases the volume for a professional resource related to multi-omics data. However, the lack of global embryogenesis repository and systematic analysis tools limits the preceding in stem cell research, human congenital diseases and assisted reproduction. Here, we developed the EmAtlas, which collects the most comprehensive multi-omics data and provides multi-scale tools to explore spatiotemporal activation during mammalian embryogenesis. EmAtlas contains data on multiple types of gene expression, chromatin accessibility, DNA methylation, nucleosome occupancy, histone modifications, and transcription factors, which displays the complete spatiotemporal landscape in mouse and human across several time points, involving gamet

SUBMITTER: Zheng L 

PROVIDER: S-EPMC9825456 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature