CellTracer: a comprehensive database to dissect the causative multilevel interplay contributing to cell development trajectories.

ABSTRACT: During the complex process of tumour development, the unique destiny of cells is driven by the fine-tuning of multilevel features such as gene expression, network regulation and pathway activation. The dynamic formation of the tumour microenvironment influences the therapeutic response and clinical outcome. Thus, characterizing the developmental landscape and identifying driver features at multiple levels will help us understand the pathological development of disease in individual cell populations and further contribute to precision medicine. Here, we describe a database, CellTracer (http://bio-bigdata.hrbmu.edu.cn/CellTracer), which aims to dissect the causative multilevel interplay contributing to cell development trajectories. CellTracer consists of the gene expression profiles of 1 94

SUBMITTER: Guo Q 

PROVIDER: S-EPMC9825461 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature