NPASS database update 2023: quantitative natural product activity and species source database for biomedical research.

ABSTRACT: Quantitative activity and species source data of natural products (NPs) are important for drug discovery, medicinal plant research, and microbial investigations. Activity values of NPs against specific targets are useful for discovering targeted therapeutic agents and investigating the mechanism of medicinal plants. Composition/concentration values of NPs in individual species facilitate the assessments and investigations of the therapeutic quality of herbs and phenotypes of microbes. Here, we describe an update of the NPASS natural product activity and species source database previously featured in NAR. This update includes: (i) new data of ∼95 000 records of the composition/concentration values of ∼1 490 NPs/NP clusters in ∼390 species, (ii) extended data of activity values of ∼43 200 NP

SUBMITTER: Zhao H 

PROVIDER: S-EPMC9825494 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature