Microbiome Toolbox: methodological approaches to derive and visualize microbiome trajectories.

ABSTRACT:

Motivation

The gut microbiome changes rapidly under the influence of different factors such as age, dietary changes or medications to name just a few. To analyze and understand such changes, we present a Microbiome Toolbox. We implemented several methods for analysis and exploration to provide interactive visualizations for easy comprehension and reporting of longitudinal microbiome data.

Results

Based on the abundance of microbiome features such as taxa as well as functional capacity modules, and with the corresponding metadata per sample, the Microbiome Toolbox includes methods for (i) data analysis and exploration, (ii) data preparation including dataset-specific preprocessing and transformation, (iii) best feature selection for log-ratio denominators, (iv) two-group anal

SUBMITTER: Banjac J 

PROVIDER: S-EPMC9825749 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature