Lung structure and function on MRI in preterm born school children with and without BPD: A feasibility study.

ABSTRACT:

Background and objective

The most common respiratory complication of prematurity is bronchopulmonary dysplasia (BPD), leading to structural lung changes and impaired respiratory outcomes. However, also preterm children without BPD may show similar adverse respiratory outcomes. There is a need for a safe imaging modality for preterm children with and without BPD for disease severity assessment and risk stratification. Our objective was to develop a magnetic resonance imaging (MRI) protocol in preterm children with and without BPD at school age.

Methods

Nine healthy volunteers (median age 11.6 [range: 8.8-12.8] years), 11 preterm children with BPD (11.0 [7.2-15.6] years), and 9 without BPD (11.1 [10.7-12.6] years) underwent MRI. Images were scored on hypo- and hyperintense abn

SUBMITTER: Elders BBLJ 

PROVIDER: S-EPMC9826116 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature