Periodontal health, cognitive decline, and dementia: A systematic review and meta-analysis of longitudinal studies.

ABSTRACT:

Background

Emerging evidence indicates that poor periodontal health adversely impacts cognition. This review examined the available longitudinal evidence concerning the effect of poor periodontal health on cognitive decline and dementia.

Methods

Comprehensive literature search was conducted on five electronic databases for relevant studies published until April 2022. Longitudinal studies having periodontal health as exposure and cognitive decline and/or dementia as outcomes were considered. Random effects pooled estimates and 95% confidence intervals were generated (pooled odds ratio for cognitive decline and hazards ratio for dementia) to assess whether poor periodontal health increases the risk of cognitive decline and dementia. Heterogeneity between studies was estimated

SUBMITTER: Asher S 

PROVIDER: S-EPMC9826143 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature