Megalo-Cavitands: Synthesis of Acridane[4]arenes and Formation of Large, Deep Cavitands for Selective C70 Uptake.

ABSTRACT: Deep cavitands, concave molecular containers, represent an important supramolecular host class that has been explored for a variety of applications ranging from sensing, switching, purification and adsorption to catalysis. A major limitation in the field has been the cavitand volume that is restricted by the size of the structural platform utilized (diameter approx. 7 Å). We here report the synthesis of a novel, unprecedentedly large structural platform, named acridane[4]arene (diameter approx. 14 Å), suitable for the construction of cavitands with volumes of up to 814 ų . These megalo-cavitands serve as size-selective hosts for fullerenes with mM to sub-μM binding affinity for C₆₀ and C₇₀ . Furthermore, the selective binding of fullerene C₇₀ in

SUBMITTER: Pfeuffer-Rooschuz J 

PROVIDER: S-EPMC9826223 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature