External Validation of e-ASPECTS Software for Interpreting Brain CT in Stroke.

ABSTRACT:

Objective

The purpose of this study was to test e-ASPECTS software in patients with stroke. Marketed as a decision-support tool, e-ASPECTS may detect features of ischemia or hemorrhage on computed tomography (CT) imaging and quantify ischemic extent using Alberta Stroke Program Early CT Score (ASPECTS).

Methods

Using CT from 9 stroke studies, we compared software with masked experts. As per indications for software use, we assessed e-ASPECTS results for patients with/without middle cerebral artery (MCA) ischemia but no other cause of stroke. In an analysis outside the intended use of the software, we enriched our dataset with non-MCA ischemia, hemorrhage, and mimics to simulate a representative "front door" hospital population. With final diagnosis as the reference standard,

SUBMITTER: Mair G 

PROVIDER: S-EPMC9826303 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature