A scoping review of statistical methods for trial-based economic evaluations: The current state of play.

ABSTRACT: The statistical quality of trial-based economic evaluations is often suboptimal, while a comprehensive overview of available statistical methods is lacking. Therefore, this review summarized and critically appraised available statistical methods for trial-based economic evaluations. A literature search was performed to identify studies on statistical methods for dealing with baseline imbalances, skewed costs and/or effects, correlated costs and effects, clustered data, longitudinal data, missing data and censoring in trial-based economic evaluations. Data was extracted on the statistical methods described, their advantages, disadvantages, relative performance and recommendations of the study. Sixty-eight studies were included. Of them, 27 (40%) assessed methods for baseline imbalances, 39

SUBMITTER: El Alili M 

PROVIDER: S-EPMC9826466 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature