Epidemiology and treatment outcomes of cutaneous squamous cell carcinoma extending to the temporal bone.

ABSTRACT:

Background

Accurate epidemiological and outcomes data regarding cutaneous squamous cell carcinoma (cSCC) extending to the temporal bone is lacking.

Methods

Retrospective analysis of 167 Australian patients with primary and peri-temporal bone cSCC.

Results

cSCC extending from secondary subsites (93.4%) was 14 times more frequent than primary temporal bone SCC (6.6%). For patients who underwent curative surgery ± post-operative radiotherapy (n = 146, 87.4%), 5-year disease-free survival, locoregional recurrence-free survival, disease-specific survival, and overall survival was 53.0%, 59.4%, 67.9%, and 44.7%, respectively. External ear and pre-auricular tumors, salvage surgery, tumor size (≥40 mm medial-lateral), nodal disease, and involved margins were negative predicto

SUBMITTER: Schachtel MJC 

PROVIDER: S-EPMC9826480 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature