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Time course of right-hemisphere recruitment during word production following left-hemisphere damage: A single case of young stroke.


ABSTRACT: Our understanding of post-stroke language function is largely based on older age groups, who show increasing age-related brain pathology and neural reorganisation. To illustrate language outcomes in the young-adult brain, we present the case of J., a 23-year-old woman with chronic aphasia from a left-hemisphere stroke affecting the temporal lobe. Diffusion MRI-based tractography indicated that J.'s language-relevant white-matter structures were severely damaged. Employing magnetoencephalography (MEG), we explored J.'s conceptual preparation and word planning abilities using context-driven and bare picture-naming tasks. These revealed naming deficits, manifesting as word-finding difficulties and semantic paraphasias about half of the time. Naming was however facilitated by semantically cons

SUBMITTER: Chupina I 

PROVIDER: S-EPMC9826534 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature