Gene polymorphisms and risk of head and neck squamous cell carcinoma: a systematic review.

ABSTRACT:

Background

Exposure to the same environmental factors in different people have resulted in different susceptibility to head and neck squamous cell carcinoma (HNSCC), which suggests genetic variation may be a risk factor for the development of HNSCC. So, the aim was to review literatures on the association between gene polymorphisms and risk of HNSCCs.

Materials and methods

This systematic review included all articles on the impact of gene polymorphisms on risk and susceptibility to HNSCC published till September 2021 using PubMed, Web of science, SCOPUS, Google Scholar and Cochrane library databases.

Results

Of 1163 initial searched articles, 77 articles were eligible to include in this review. Studies were categorized based on gene functions. In each category, studie

SUBMITTER: Rajabi-Moghaddam M 

PROVIDER: S-EPMC9826653 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature