CMR-based right ventricular strain analysis in cardiac amyloidosis and its potential as a supportive diagnostic feature.

ABSTRACT:

Background

Right ventricular (RV) strain has provided valuable prognostic information for patients with cardiac amyloidosis (CA). However, the extent to which RV strain and strain rate can differentiate CA is not yet clinically established. CA underdiagnosis delays treatment strategies and exacerbates patient prognosis.

Aims

Evaluation of cardiac magnetic resonance (CMR) quantified RV global and regional strain of CA and HCM patients along with CA subtypes.

Methods

CMR feature tracking attained longitudinal, radial and circumferential global and regional strain in 47 control subjects (CTRL), 43 CA-, 20 hypertrophic cardiomyopathy- (HCM) patients. CA patients were subdivided in 21 transthyretin-related amyloidosis (ATTR) and 20 acquired immunoglobulin light chain (AL)

SUBMITTER: Eckstein J 

PROVIDER: S-EPMC9827025 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature