Validation of a paediatric sepsis screening tool to identify children with sepsis in the emergency department: a statewide prospective cohort study in Queensland, Australia.

ABSTRACT:

Objective

The Surviving Sepsis Campaign guidelines recommend the implementation of systematic screening for sepsis. We aimed to validate a paediatric sepsis screening tool and derive a simplified screening tool.

Design

Prospective multicentre study conducted between August 2018 and December 2019. We assessed the performance of the paediatric sepsis screening tool using stepwise multiple logistic regression analyses with 10-fold cross-validation and evaluated the final model at defined risk thresholds.

Setting

Twelve emergency departments (EDs) in Queensland, Australia.

Participants

3473 children screened for sepsis, of which 523 (15.1%) were diagnosed with sepsis.

Interventions

A 32-item paediatric sepsis screening tool including rapidly available inform

SUBMITTER: Gilholm P 

PROVIDER: S-EPMC9827183 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature