Factors influencing participation in randomised clinical trials among patients with early Barrett's neoplasia: a multicentre interview study.

ABSTRACT:

Objectives

Strong recruitment and retention into randomised controlled trials involving invasive therapies is a matter of priority to ensure better achievement of trial aims. The BRIDE (Barrett's Randomised Intervention for Dysplasia by Endoscopy) Study investigated the feasibility of undertaking a multicentre randomised controlled trial comparing argon plasma coagulation and radiofrequency ablation, following endoscopic resection, for the management of early Barrett's neoplasia. This paper aims to identify factors influencing patients' participation in the BRIDE Study and determine their views regarding acceptability of a potential future trial comparing surgery with endotherapy.

Design

A semistructured telephone interview study was performed, including both patients who ac

SUBMITTER: Peerally MF 

PROVIDER: S-EPMC9827249 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature