Are non-invasive or minimally invasive autopsy techniques for detecting cause of death in prenates, neonates and infants accurate? A systematic review of diagnostic test accuracy.

ABSTRACT:

Objectives

To assess the diagnostic accuracy of non-invasive or minimally invasive autopsy techniques in deaths under 1 year of age.

Design

This is a systematic review of diagnostic test accuracy. The protocol is registered on PROSPERO.

Participants

Deaths from conception to one adjusted year of age.

Search methods

MEDLINE (Ovid), EMBASE (Ovid), CINAHL (EBSCO), the Cochrane Library, Scopus and grey literature sources were searched from inception to November 2021.

Diagnostic tests

Non-invasive or minimally invasive diagnostic tests as an alternative to traditional autopsy.

Data collection and analysis

Studies were included if participants were under one adjusted year of age, with index tests conducted prior to the reference standard.Data were extra

SUBMITTER: O'Keefe H 

PROVIDER: S-EPMC9827258 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature