Belief Updating and Paranoia in Individuals With Schizophrenia.

ABSTRACT:

Background

Persecutory delusions are among the most common delusions in schizophrenia and represent the extreme end of the paranoia continuum. Paranoia is accompanied by significant worry and distress. Identifying cognitive mechanisms underlying paranoia is critical for advancing treatment. We hypothesized that aberrant belief updating, which is related to paranoia in human and animal models, would also contribute to persecutory beliefs in individuals with schizophrenia.

Methods

Belief updating was assessed in 42 participants with schizophrenia and 44 healthy control participants using a 3-option probabilistic reversal learning task. Hierarchical Gaussian Filter was used to estimate computational parameters of belief updating. Paranoia was measured using the Positive and Neg

SUBMITTER: Sheffield JM 

PROVIDER: S-EPMC9827723 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature