End-stage renal disease incidence in a cohort of US firefighters from San Francisco, Chicago, and Philadelphia.

ABSTRACT:

Background

Firefighters perform strenuous work in hot environments, which may increase their risk of chronic kidney disease. The purpose of this study was to evaluate the risk of end-stage renal disease (ESRD) and types of ESRD among a cohort of US firefighters compared to the US general population, and to examine exposure-response relationships.

Methods

ESRD from 1977 through 2014 was identified through linkage with Medicare data. ESRD incidence in the cohort compared to the US population was evaluated using life table analyses. Associations of all ESRD, systemic ESRD, hypertensive ESRD, and diabetic ESRD with exposure surrogates (exposed days, fire runs, and fire hours) were examined in Cox proportional hazards models adjusted for attained age (the time scale), race, birth

SUBMITTER: Pinkerton LE 

PROVIDER: S-EPMC9828160 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature