Osa-miR160a confers broad-spectrum resistance to fungal and bacterial pathogens in rice.

ABSTRACT: Rice production is threatened by multiple pathogens. Breeding cultivars with broad-spectrum disease resistance is necessary to maintain and improve crop production. Previously we found that overexpression of miR160a enhanced rice blast disease resistance. However, it is unclear whether miR160a also regulates resistance against other pathogens, and what the downstream signaling pathways are. Here, we demonstrate that miR160a positively regulates broad-spectrum resistance against the causative agents of blast, leaf blight and sheath blight in rice. Mutations of miR160a-targeted Auxin Response Factors result in different alteration of resistance conferred by miR160a. miR160a enhances disease resistance partially by suppressing ARF8, as mutation of ARF8 in MIM160 background partially restores

SUBMITTER: Feng Q 

PROVIDER: S-EPMC9828417 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature