Influence of bronchopulmonary dysplasia on lung function in adolescents who were born extremely prematurely.

ABSTRACT:

Objectives

To assess if a previous diagnosis of bronchopulmonary dysplasia (BPD) was associated with poorer lung function at 16 to 19 years of age, regardless of whether postnatal corticosteroids had been administered.

Working hypothesis

Infants with BPD will have poorer lung function at 16 to 19 years of age.

Study design

Prospective follow-up study.

Patient-subject selection

One hundred and sixty-one participants aged between 16 and 19 years who were born at less than 29 weeks of gestation; 87 had had BPD.

Methodology

Lung function was assessed by spirometry (FEV₁ , FVC, FEV₁ /FVC, FEF₇₅ , FEF₅₀ , FEF₂₅ , FEF_{25 -75} , PEF), impulse oscillometry (R5Hz and R20Hz), plethysmography

SUBMITTER: Harris C 

PROVIDER: S-EPMC9828792 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature