Impact of Antibiotic Time-Outs in Multidisciplinary ICU Rounds for Antimicrobial Stewardship Program on Patient Survival: A Controlled Before-and-After Study.

ABSTRACT: The antimicrobial stewardship program (ASP) is an important quality improvement initiative that is recommended in the ICU. However, the shortage of infectious disease physicians in Japan has led to the need for simpler methods for implementing ASPs. We investigated whether antibiotic time-outs (ATOs) during multidisciplinary rounds as part of an ASP can improve patient survival and reduce the number of days of therapy (DOT) with antibiotics.

Design

Single-center controlled before-and-after study.

Setting

Medical/surgical ICU in a tertiary university medical center in Tokyo, Japan.

Patients

All patients 16 years old or older admitted consecutively in the ICU between October 2016 and March 2020.

Interventions

An intensivist-driven ICU multidisciplinary round was i

SUBMITTER: Mishima Y 

PROVIDER: S-EPMC9829256 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature