Investigation of anti-galectin-8 levels in patients with multiple sclerosis: A consort-clinical study.

ABSTRACT:

Background

Galectins are a family of endogenous mammalian lectins involved in pathogen recognition, killing, and facilitating the entry of microbial pathogens and parasites into the host. They are the intermediators that decipher glycan-containing information about the host immune cells and microbial structures to modulate signaling events that cause cellular proliferation, chemotaxis, cytokine secretion, and cell-to-cell communication. They have subgroups that take place in different roles in the immune system. The effect of galectin-8 on multiple sclerosis disease (MS) has been studied in the literature, but the results seemed unclear. In this study, we aimed to determine anti-galectin-8 (anti-Gal-8) levels in MS and their potential use as biomarkers.

Methods

In this exper

SUBMITTER: Cinkir U 

PROVIDER: S-EPMC9829274 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature