Development of fatty acid metabolism-related models in lung adenocarcinomaA Review.

ABSTRACT:

Backgroud

Lung adenocarcinoma (LUAD) is 1 of the common malignancy with a poor prognosis.

Materials and methods

Based on bioinformatics, the fatty acid metabolism model of LUAD was developed. We downloaded LUAD transcriptome data from the cancer genome atlas and gene expression omnibus databases. We used bioinformatics methods to construct a fatty acid metabolism-related predictive risk model to predict the prognosis of LUAD. We further explored the relationship between prognostic models and survival and immunity.

Results

We identified 17 prognosis-related fatty acid-associated genes and constructed prognostic models. In the the cancer genome atlas cohort, the prognosis was worse in the high-risk score group compared to the low-risk score group. The ROC curve confirme

SUBMITTER: Ye W 

PROVIDER: S-EPMC9829279 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature