Systemic oncological treatments in patients with advanced pancreatic cancer: a scoping review and evidence map.

ABSTRACT:

Purpose

To identify, describe, and organise currently available evidence regarding systemic oncological treatments (SOTs) (chemotherapy, targeted/biological therapies, and immunotherapy) compared to best supportive care (BSC) for patients with advanced pancreatic cancer (PC).

Methods

We conducted a scoping review and evidence mapping, adhering to PRISMA-ScR checklist. We searched MEDLINE, EMBASE, Cochrane Library, Epistemonikos, PROSPERO, and clinicaltrials.gov for eligible studies. We included systematic reviews (SRs), randomised controlled trials (RCTs), quasi-experimental, and observational studies evaluating SOTs compared to BSC or no treatment in patients with advanced PC. Two independent reviewers performed the screening process and data extraction. We developed eviden

SUBMITTER: Salazar J 

PROVIDER: S-EPMC9829581 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature