Cardiovascular risk-enhancing factors and coronary artery calcium in South Asian American adults: The MASALA study.

ABSTRACT:

Objectives

The 2018 and 2019 U.S. guidelines for the management of cholesterol and primary prevention of atherosclerotic cardiovascular disease (ASCVD) recommend consideration of cardiovascular risk-enhancing factors (REFs), including South Asian ancestry, to refine ASCVD risk estimation. However, the associations of REFs with atherosclerosis are unclear in South Asian American adults, who have a disproportionately elevated premature coronary heart disease risk. In the Mediators of Atherosclerosis in South Asians Living in America (MASALA) cohort, we investigated associations of individual REFs, or the number of REFs, with coronary artery calcium (CAC).

Methods

Using baseline and follow-up data from MASALA, we evaluated the association of REFs (family history of ASCVD, low-d

SUBMITTER: Shah H 

PROVIDER: S-EPMC9830105 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature