Expression and clinical significance of miR-17-5p in tumor tissues of patients with colorectal cancer.

ABSTRACT:

Background

At present, there is a lack of novel biomarkers for the early diagnosis and targeted therapy of colorectal cancer (CRC). The current study investigated the expression of miR-17-5p in colorectal tumors and adjacent tissues, and examined the effects of miR-17-5p on the cellular growth of the colon cancer cell line HCT-116.

Methods

A total of 30 paired tissue specimens were obtained from patients with CRC who were admitted to the Department of General Surgery V of the First Affiliated Hospital, Gannan Medical College between December 2019 and January 2021. The clinical information for the corresponding patients was collated. Real-time fluorescence quantitative polymerase chain reaction (RT-qPCR) was performed to detect the expression of miR-17-5p in tumor tissues and

SUBMITTER: Liu Z 

PROVIDER: S-EPMC9830340 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature