Adjuvant treatment for the elderly patient with resected gallbladder cancer: a SEER-Medicare analysis.

ABSTRACT:

Background

In patients with resected gallbladder cancer (GBC), the role of adjuvant chemotherapy (aCT) remains ill-defined, especially in elderly patients. This study evaluates the value of aCT in elderly patients with GBC and assesses response according to tumor stage.

Methods

Patients of ≥65 years of age with resected GBC diagnosed from 2004-2015 were identified using a Surveillance, Epidemiology and End Results (SEER)/Medicare linked database. After propensity score matching, survival of patients treated with aCT was compared to survival of patients who did not receive aCT using Kaplan-Meier and Cox proportional hazards analysis.

Results

Of 2,179 patients with resected GBC, 876 (25%) received aCT. In the full cohort of 810 propensity-score matched patients, surviva

SUBMITTER: de Savornin Lohman E 

PROVIDER: S-EPMC9830355 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature