Altered engagement of the speech motor network is associated with reduced phonological working memory in autism.

ABSTRACT: Nonword repetition, a common clinical measure of phonological working memory, involves component processes of speech perception, working memory, and speech production. Autistic children often show behavioral challenges in nonword repetition, as do many individuals with communication disorders. It is unknown which subprocesses of phonological working memory are vulnerable in autistic individuals, and whether the same brain processes underlie the transdiagnostic difficulty with nonword repetition. We used functional magnetic resonance imaging (fMRI) to investigate the brain bases for nonword repetition challenges in autism. We compared activation during nonword repetition in functional brain networks subserving speech perception, working memory, and speech production between neurotypical and

SUBMITTER: O'Brien AM 

PROVIDER: S-EPMC9830373 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature