Long-term pelvic fracture and overall mortality risk after pelvic cancer and pelvic radiation.

ABSTRACT:

Background

The association of pelvic radiation with pelvic fracture risk has not been examined in prospective cohort settings with comprehensive fracture risk assessment, cancer-free comparison populations, and long-term follow-up. Our objective is to better characterize pelvic fracture and overall mortality risks in postmenopausal women participating in the Women's Health Initiative.

Methods

A total of 135 743 Women's Health Initiative participants aged 50 to 79 years enrolled from 40 US clinical centers from 1993 to 1998 who had entry Fracture Risk Assessment Tool scores were eligible. Outcomes included pelvic cancer diagnosis, pelvic fracture occurrence, and mortality. Cox proportional hazards regression models were used to examine associations of pelvic cancer and pelvic

SUBMITTER: Nelson RA 

PROVIDER: S-EPMC9830483 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature