Lipoprotein Insulin Resistance Index: A Simple, Accurate Method for Assessing Insulin Resistance in South Asians.

ABSTRACT:

Context

Identification of insulin resistance (IR) in South Asians, who are at a higher risk for type 2 diabetes, is important. Lack of standardization of insulin assays limits the clinical use of insulin-based surrogate indices. The lipoprotein insulin resistance index (LP-IR), a metabolomic marker, reflects the lipoprotein abnormalities observed in IR. The reliability of the LP-IR index in South Asians is unknown.

Objective

We evaluated the predictive accuracy of LP-IR compared with other IR surrogate indices in South Asians.

Methods

In a cross-sectional study (n = 55), we used calibration model analysis to assess the ability of the LP-IR score and other simple surrogate indices (Homeostatic Model Assessment of Insulin Resistance, Quantitative insulin sensitivity che

SUBMITTER: Fosam A 

PROVIDER: S-EPMC9830979 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature