Contribution of Shape Features to Intradiscal Pressure and Facets Contact Pressure in L4/L5 FSUs: An In-Silico Study.

ABSTRACT: Finite element models (FEMs) of the spine commonly use a limited number of simplified geometries. Nevertheless, the geometric features of the spine are important in determining its FEM outcomes. The link between a spinal segment's shape and its biomechanical response has been studied, but the co-variances of the shape features have been omitted. We used a principal component (PCA)-based statistical shape modelling (SSM) approach to investigate the contribution of shape features to the intradiscal pressure (IDP) and the facets contact pressure (FCP) in a cohort of synthetic L4/L5 functional spinal units under axial compression. We quantified the uncertainty in the FEM results, and the contribution of individual shape modes to these results. This parameterisation approach is able to capture

SUBMITTER: Kassab-Bachi A 

PROVIDER: S-EPMC9831962 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature