Suppression of seizure in childhood absence epilepsy using robust control of deep brain stimulation: a simulation study.

ABSTRACT: Deep brain stimulation (DBS) is a promising technique to relieve the symptoms in patients with intractable seizures. Although the DBS therapy for seizure suppression dates back more than 40 years, determining stimulation parameters is a significant challenge to the success of this technique. One solution to this challenge with application in a real DBS system is to design a closed-loop control system to regulate the stimulation intensity using computational models of epilepsy automatically. The main goal of the current study is to develop a robust control technique based on adaptive fuzzy terminal sliding mode control (AFTSMC) for eliminating the oscillatory spiking behavior in childhood absence epilepsy (CAE) dynamical model consisting of cortical, thalamic relay, and reticular nuclei neu

SUBMITTER: Rouhani E 

PROVIDER: S-EPMC9832016 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature