Ontology highlight
ABSTRACT:
SUBMITTER: Bennetts FM
PROVIDER: S-EPMC9832217 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature
Bennetts Felix M FM Mobbs Jesse I JI Ventura Sabatino S Thal David M DM
Purinergic signalling 20220711 4
Within the family of purinergic receptors, the P2X1 receptor is a ligand-gated ion channel that plays a role in urogenital, immune and cardiovascular function. Specifically, the P2X1 receptor has been implicated in controlling smooth muscle contractions of the vas deferens and therefore has emerged as an exciting drug target for male contraception. In addition, the P2X1 receptor contributes to smooth muscle contractions of the bladder and is a target to treat bladder dysfunction. Finally, platel ...[more]