YopB of Yersinia enterocolitica is essential for YopE translocation.

ABSTRACT: A previous study has shown that YopB of Yersinia spp. is essential for translocation of Yop effectors across the eucaryotic plasma membrane (M.-P. Sory and G. R. Cornelis, Mol. Microbiol. 14:583--594, 1994). However, this role was recently challenged (V. T. Lee and O. Schneewind, Mol. Microbiol. 31:1619--1629, 1999). Using protease protection and digitonin extraction, we reconfirm that YopB of Yersinia enterocolitica is essential for the translocation of YopE into HeLa cell monolayers.

SUBMITTER: Nordfelth R 

PROVIDER: S-EPMC98323 | biostudies-literature | 2001 May

REPOSITORIES: biostudies-literature