Highly sensitive pork meat detection using copper(ii) tetraaza complex by electrochemical biosensor.

ABSTRACT: Three copper(ii) tetraaza complexes [Cu(ii)LBr]Br (1a), [Cu(ii)L(CIO₄)](CIO₄) (2a) and [Cu(ii)L](CIO₄)₂ (2b), where L = 5,5,7,12,12,14-hexamethyl-1,4,8,11-tetraazacyclotetradeca-7,14-diene were prepared and confirmed by FTIR, ¹HNMR and ¹³CNMR. The binding interaction of complex (1a, 2a, 2b) with calf thymus DNA (CT-DNA) was investigated using UV-vis absorption, luminescence titrations, viscosity measurements and molecular docking. The findings suggested that complex 1a, 2a and 2b bind to DNA by electrostatic interaction, and the strengths of the interaction were arranged according to 2b > 1a > 2a. The differences in binding strengths were certainly caused by the complexes' dissimilar charges and counter anions. Complex 2b, w

SUBMITTER: Jilani NAK 

PROVIDER: S-EPMC9832347 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature