Retrograde reperfusion of renal grafts to reduce ischemic-reperfusion injury.

ABSTRACT:

Background

During transplantation, a kidney graft undergoes a cascade of pathological changes, referred to as ischemia-reperfusion injury (IRI), as it is incorporated into the bloodstream. Various studies have reported that retrograde reperfusion (RRP) leads to improved myocardial recovery and could reduce IRI in liver transplantation. This study investigated the effect of RRP in renal transplantation with a focus on reduction of kidney IRI.

Methods

Between December 2019 and July 2022, 15 consecutive kidney transplants were performed with retrograde venous reperfusion. To conduct a comparative study and to recruit a control group, 15 kidney transplants that had been performed in the same center by the same two surgeons were retrospectively analyzed. Differences between the t

SUBMITTER: Rysmakhanov M 

PROVIDER: S-EPMC9832596 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature