The characteristics of mRNA m⁶A methylomes in allopolyploid Brassica napus and its diploid progenitors.

ABSTRACT: Genome duplication events, comprising whole-genome duplication and single-gene duplication, produce a complex genomic context leading to multiple levels of genetic changes. However, the characteristics of m⁶A modification, the most widespread internal eukaryotic mRNA modification, in polyploid species are still poorly understood. This study revealed the characteristics of m⁶A methylomes within the early formation and following the evolution of allopolyploid Brassica napus. We found a complex relationship between m⁶A modification abundance and gene expression level depending on the degree of enrichment or presence/absence of m⁶A modification. Overall, the m⁶A genes had lower gene expression levels than the non-m⁶A gene

SUBMITTER: Li Z 

PROVIDER: S-EPMC9832873 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature