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Urine ketone bodies and adverse outcomes in patients with acute ischemic stroke or TIA.


ABSTRACT:

Background and aims

Urine ketone bodies have been considered as predictors of stroke in diabetic patients, however, the role of urine ketone bodies in the prognosis of stroke has not been investigated well. This study aimed to investigate the association between urine ketone bodies and adverse outcomes in patients with acute ischemic stroke (AIS) or transient ischemic attack (TIA).

Methods

This study enrolled 14 015 patients with AIS or TIA who screened for urine ketone bodies from the Third China National Stroke Registry. Status of urine ketone bodies were classified into negative, suspicious positive and positive. The outcomes were all-cause death and poor functional outcomes (modified Rankin Scale [mRS] 2-6/3-6) at 3 months and 1 year. Multivariable Cox proportional hazar

SUBMITTER: Wang A 

PROVIDER: S-EPMC9833217 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature